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标题: MRI6255：三博20-07，男性，20岁。颈部疼痛2月，腰部臀部疼痛 [打印本页]

作者: 翁志蓬 时间: 2014-1-26 18:10
标题: MRI6255：三博20-07，男性，20岁。颈部疼痛2月，腰部臀部疼痛
【结果公布】
第二十期三博读片会病例之七
卫生部北京医院放射科陈涓提供
男性，20岁。
颈部疼痛2月，腰部臀部疼痛1月。

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作者: bin917 时间: 2014-1-26 21:27
嗜酸性肉芽肿

作者: xiongneo 时间: 2014-1-26 22:01
脊索瘤？

作者: GAOSHENGJIANG 时间: 2014-1-27 09:50
病变分布广泛，骨质有侵蚀破坏，个别椎体变扁，上颌窦有炎性改变，符合炎性肉芽肿改变。

作者: 施明 时间: 2014-1-29 08:34
转移瘤

作者: 难听 时间: 2014-1-31 19:48
伴有颈部多发淋巴结增大，考虑白血病可能，淋巴瘤待排。

作者: 翁志蓬 时间: 2014-2-3 20:34
标题: 诊断及点评
前臂肿物活检，病理报告：小圆细胞恶性肿瘤，免疫组化考虑为PNET/尤文氏肉瘤。

【点评】
Primitive neuroectodermal tumor (PNET) , a subtype of the family of small round cell malignancies with neuroectodermal origin, was first described in 1918 by Stout.
This highly malignant tumor can further be divided into central PNET (cPNET) and peripheral PNET (pPNET). The PNET
Peripheral PNET occurs outside the central and sympathetic nervous system, often occurs in the thoracopulmonary region (Askin tumor),retroperitonium, and extremities and rarely in the head and neck.
Recent studies showed that pPNET and ES have
many similarities in histomorphology,
immunohistochemistry, and molecular biology. They
are grouped as the ES/PNET family and are difficult
to distinguish from each.
Peripheral PNET mainly affects children and adolescents and rarely adults.
female/ male predominance?
Patients often presented with rapidly enlarging masses.
The imaging features of pPNET of the head and neck
are nonspecific.
In pPNET patients with tumors originating from soft tissues, the tumors often demonstrated ill-defined,soft tissue masses and exhibited aggressive spreading to the neighboring tissue.
The tumor often demonstrated isodensity with patchyhypodensity areas on unenhanced CT images.
On T1WI, the tumor demonstrated isointensity or slightly hypointensity; on T2WI, the tumor demonstrated heterogeneous hyperintensity.
The tumor demonstrated heterogeneous enhancement on contrast-enhanced CT/T1WI.
Calcification is rare.
Cystic necrotic component and haemorrhagic change are usually obvious.
Poor prognosis. The overall 5-year survival rates for localized and metastatic tumours range from 65% to 74% and 25% to 45%, respectively.

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作者: shibing 时间: 2014-2-4 01:43
小圆细胞恶性肿瘤，

作者: pujunzhi 时间: 2014-2-4 10:40
前臂肿物活检，病理报告：小圆细胞恶性肿瘤，免疫组化考虑为PNET/尤文氏肉瘤。
好病例，谢谢翁总的精彩点评！

作者: 拾荒者 时间: 2014-3-20 21:51
谢谢！要是点评用汉语就更好了！

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